
NAD+
Ships fully reconstituted · no mixing, no powder, no bacteriostatic waterThe Cellular Energy Coenzyme
Replenishes a vital coenzyme for DNA repair, energy production, and longevity.
Choose your supply
Extra 10% off your first order · use code WELCOME10 at checkout (stacks with the supply discount above).
Frequently paired with
What it supports
- Restores cellular energy production
- Supports DNA repair and genomic stability
- Enhances mitochondrial function
- Improves cognitive clarity and focus
- Activates sirtuin longevity pathways
- May reduce age-related fatigue
- Supports immune cell function
The details
- Administration
- Subcutaneous injection
- Format
- 100 mg/mL, 10 mL vial
- Typical dosing
- Per provider guidance, subcutaneous injection
- Best for
- Cellular energy, DNA repair, anti-aging
- Pairs well with
- Epitalon, MOTS-C, Thymosin Alpha-1
- Mechanism
- NAD+ fuels sirtuins (SIRT1-7) and PARPs — enzymes responsible for DNA repair, gene expression regulation, and mitochondrial biogenesis. Replenishing NAD+ restores cellular energy production, activates longevity pathways, and supports the body's natural repair mechanisms.
How it works
Signal
NAD+ is given as a subcutaneous injection on a provider-determined schedule — the SubQ route bypasses the gut for higher bioavailability than oral NMN or NR.
Cellular response
NAD+ fuels sirtuins (SIRT1–7) and PARPs — the enzymes responsible for DNA repair, gene-expression regulation, and mitochondrial biogenesis. Replenishing it restores cellular energy production, activates longevity pathways, and supports the body's natural repair mechanisms.
Outcome
Over the following weeks most people notice morning energy and focus first (weeks 1–2), then sharper cognition and faster workout recovery (weeks 2–4), then steadier all-day energy and more restorative sleep as restoration reaches more tissues (weeks 4–8).
Sources & references
NAD+ decline as a driver of cellular aging
Imai S & Guarente L. Trends Cell Biol. 2014;24(8):464–471.
View sourceNAD+ boosting: the in vivo evidence
Rajman L et al. Cell Metab. 2018;27(3):529–547.
View sourceNAD+ in regenerative medicine (review)
Conlon N. Plast Reconstr Surg. 2022.
View sourceNAD+ decline with age and metabolic dysfunction
Cell Metabolism, 2018
View sourceNAD+ precursor supplementation in humans
Nature Communications, 2018
View sourceSirtuins, NAD+ and mitochondrial function
Cell, 2016
View sourceNAD+ therapeutics in neurodegeneration
Neuron, 2020
View source
Common questions
Important safety information
NAD+ is available by prescription only and is dispensed after a licensed provider reviews your medical screening and determines it is appropriate for you. Compounded medications are prepared by a licensed U.S. pharmacy and are not FDA-approved products. Tell your provider about your full medical history and any medications you take.
- • Generally well tolerated
- • May cause mild injection site irritation
- • Should be administered under licensed provider supervision
- • Monitor in patients with active malignancies


