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Ships fully reconstituted · no mixing, no powder, no bacteriostatic water
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NAD+
Anti-Aging

NAD+

Ships fully reconstituted · no mixing, no powder, no bacteriostatic water

The Cellular Energy Coenzyme

Replenishes a vital coenzyme for DNA repair, energy production, and longevity.

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Physician-reviewed · charged only after your prescription is approved
Free shipping over $350 · compounded in a U.S. pharmacy
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Frequently paired with

What it supports

  • Restores cellular energy production
  • Supports DNA repair and genomic stability
  • Enhances mitochondrial function
  • Improves cognitive clarity and focus
  • Activates sirtuin longevity pathways
  • May reduce age-related fatigue
  • Supports immune cell function

The details

Administration
Subcutaneous injection
Format
100 mg/mL, 10 mL vial
Typical dosing
Per provider guidance, subcutaneous injection
Best for
Cellular energy, DNA repair, anti-aging
Pairs well with
Epitalon, MOTS-C, Thymosin Alpha-1
NAD+ fuels sirtuins (SIRT1-7) and PARPs — enzymes responsible for DNA repair, gene expression regulation, and mitochondrial biogenesis. Replenishing NAD+ restores cellular energy production, activates longevity pathways, and supports the body's natural repair mechanisms.

How it works

Signal

NAD+ is given as a subcutaneous injection on a provider-determined schedule — the SubQ route bypasses the gut for higher bioavailability than oral NMN or NR.

Cellular response

NAD+ fuels sirtuins (SIRT1–7) and PARPs — the enzymes responsible for DNA repair, gene-expression regulation, and mitochondrial biogenesis. Replenishing it restores cellular energy production, activates longevity pathways, and supports the body's natural repair mechanisms.

Outcome

Over the following weeks most people notice morning energy and focus first (weeks 1–2), then sharper cognition and faster workout recovery (weeks 2–4), then steadier all-day energy and more restorative sleep as restoration reaches more tissues (weeks 4–8).

Research highlights

Studies demonstrate age-related NAD+ decline is reversible with supplementation

Research shows sirtuin activation and improved mitochondrial function

Trials on cognitive improvement and neuroprotection

Emerging data on healthspan and longevity extension

Research summaries are provided for educational context and are not a promise of results. Talk with your provider about what to expect.

Sources & references

  • NAD+ decline as a driver of cellular aging

    Imai S & Guarente L. Trends Cell Biol. 2014;24(8):464–471.

    View source
  • NAD+ boosting: the in vivo evidence

    Rajman L et al. Cell Metab. 2018;27(3):529–547.

    View source
  • NAD+ in regenerative medicine (review)

    Conlon N. Plast Reconstr Surg. 2022.

    View source

Common questions

Important safety information

NAD+ is available by prescription only and is dispensed after a licensed provider reviews your medical screening and determines it is appropriate for you. Compounded medications are prepared by a licensed U.S. pharmacy and are not FDA-approved products. Tell your provider about your full medical history and any medications you take.

  • Generally well tolerated
  • May cause mild injection site irritation
  • Should be administered under licensed provider supervision
  • Monitor in patients with active malignancies