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Ships fully reconstituted · no mixing, no powder, no bacteriostatic water
All peptides
CJC-1295/Ipamorelin
Growth Hormone

CJC-1295/Ipamorelin

Ships fully reconstituted · no mixing, no powder, no bacteriostatic water

Pulsatile Growth Hormone Release

Gold-standard GH combo for synergistic fat loss, muscle gain, and deeper sleep.

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Physician-reviewed · charged only after your prescription is approved
Free shipping over $350 · compounded in a U.S. pharmacy
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Frequently paired with

What it supports

  • Enhanced fat loss especially visceral fat
  • Increased lean muscle mass
  • Improved strength and exercise capacity
  • Better sleep quality and deeper REM cycles
  • Enhanced recovery from training
  • Supports metabolic function
  • Clean GH release with minimal side effects

The details

Administration
Subcutaneous injection, evening
Format
1.2mg/mL, 5mL vial
Typical dosing
CJC-1295 1-2mg + Ipamorelin 200-300mcg subcutaneously before bed
Best for
Body composition, fat loss, muscle gain, sleep
Pairs well with
Sermorelin, MOTS-C
CJC-1295 (no-DAC, Modified GRF 1-29) binds GHRH receptors with a short, roughly 30-minute action that primes the pituitary while keeping release pulsatile. Ipamorelin selectively binds ghrelin receptors to trigger a clean GH pulse without affecting cortisol or prolactin. The dual-pathway approach amplifies natural GH output while preserving the body's feedback mechanisms.

How it works

Signal

CJC-1295/Ipamorelin is given as a single subcutaneous injection in the evening, on an empty stomach — the timing stacks the peptide-driven pulse on top of your natural nighttime GH release.

Cellular response

CJC-1295 binds GHRH receptors with an extended half-life for continuous GH stimulation; Ipamorelin selectively binds ghrelin receptors to add clean GH pulses without raising cortisol or prolactin. Together the two pathways amplify natural GH output while preserving the body’s feedback rhythm.

Outcome

Over the following weeks most people notice deeper sleep first (weeks 1–2), then faster recovery and early fat loss (weeks 3–6), then visible body-composition changes (weeks 6–10). Your provider rechecks IGF-1 along the way to keep you in a healthy range.

Research highlights

Studies show significant increase in IGF-1 levels

Research demonstrates improved body composition

High selectivity for GH release without affecting other hormones

Well-tolerated in clinical trials with excellent safety profile

Research summaries are provided for educational context and are not a promise of results. Talk with your provider about what to expect.

Sources & references

  • Sustained GH and IGF-1 elevation in humans (CJC-1295)

    Teichman SL et al. J Clin Endocrinol Metab. 2006;91(3):799–805.

    View source
  • Ipamorelin: the first selective GH secretagogue

    Raun K et al. Eur J Endocrinol. 1998;139(5):552–561.

    View source
  • GH secretagogues and body composition (review)

    Sigalos JT & Pastuszak AW. Peptide therapeutics review, 2020.

    View source

Common questions

Important safety information

CJC-1295/Ipamorelin is available by prescription only and is dispensed after a licensed provider reviews your medical screening and determines it is appropriate for you. Compounded medications are prepared by a licensed U.S. pharmacy and are not FDA-approved products. Tell your provider about your full medical history and any medications you take.

  • May cause temporary water retention
  • Possible injection site reactions
  • Should not be used with active cancer
  • Requires licensed provider supervision