Tesamorelin
Ships fully reconstituted · no mixing, no powder, no bacteriostatic waterMetabolic Optimization Peptide
Targets visceral fat reduction through natural growth hormone stimulation.
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Frequently paired with
What it supports
- Reduces visceral (abdominal) fat
- Improves metabolic function
- Preserves lean muscle mass
- Enhances body composition
- Supports healthy lipid profiles
- Increases energy levels
- Improves overall vitality
The details
- Administration
- Subcutaneous injection
- Format
- 2mg/mL, 5mL vial
- Typical dosing
- 2mg subcutaneously daily
- Best for
- Visceral fat reduction, body composition
- Pairs well with
- Ipamorelin, MOTS-C
How it works
Signal
Tesamorelin is given as a single daily subcutaneous injection — usually in the morning — on a provider-determined schedule.
Cellular response
Tesamorelin binds GHRH receptors in the pituitary gland, triggering the natural release of growth hormone. That promotes lipolysis (fat breakdown) particularly in visceral fat deposits, while preserving subcutaneous fat and lean muscle mass.
Outcome
Over the following weeks most people notice small energy and sleep changes first (weeks 1–2), then a looser waistband and better recovery (weeks 3–6), then measurable waist-circumference reduction and improved bloodwork (weeks 6–12). Your provider may check IGF-1 along the way.
Research highlights
FDA-approved for HIV-associated lipodystrophy
Clinical studies show significant reduction in visceral fat
Research demonstrates improved triglyceride levels
Well-established safety profile from clinical trials
Research summaries are provided for educational context and are not a promise of results. Talk with your provider about what to expect.
Sources & references
Significant visceral fat reduction
Falutz J et al. J Clin Endocrinol Metab. 2004.
View sourcePivotal Phase III trial
Falutz J et al. N Engl J Med. 2007;357:2359–2370.
View sourceLong-term metabolic effects
Stanley TL et al. HIV Med. 2018.
View source
Common questions
Important safety information
Tesamorelin is available by prescription only and is dispensed after a licensed provider reviews your medical screening and determines it is appropriate for you. Compounded medications are prepared by a licensed U.S. pharmacy and are not FDA-approved products. Tell your provider about your full medical history and any medications you take.
- • Generally well-tolerated with minimal side effects
- • May cause temporary injection site reactions
- • Should not be used during pregnancy or breastfeeding
- • Requires licensed provider supervision and monitoring