GHK-Cu
Ships fully reconstituted · no mixing, no powder, no bacteriostatic waterThe Skin Rejuvenation Peptide
Boosts collagen production and skin regeneration for visible anti-aging results.
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Frequently paired with
What it supports
- Stimulates collagen and elastin production
- Reduces appearance of fine lines and wrinkles
- Improves skin firmness and elasticity
- Promotes wound healing and tissue repair
- Reduces skin inflammation
- Enhances skin radiance and glow
- Antioxidant protection for skin cells
The details
- Administration
- Subcutaneous injection
- Format
- 3mg/mL, 5mL vial
- Typical dosing
- Topical application or subcutaneous injection per provider guidance
- Best for
- Collagen, skin firmness, tissue renewal
- Pairs well with
- BPC-157, Epitalon, NAD+
- Mechanism
- GHK-Cu activates genes involved in tissue remodeling and repair. It stimulates collagen and elastin production, promotes angiogenesis (new blood vessel formation), and has anti-inflammatory properties. The copper component is essential for enzyme function in skin repair.
How it works
Signal
GHK-Cu is given as a subcutaneous injection on a provider-determined schedule — the SubQ route delivers a full therapeutic dose systemically, reaching skin, connective tissue, and hair follicles, not just the surface a topical serum touches.
Cellular response
GHK-Cu activates genes involved in tissue remodeling and repair. It stimulates collagen and elastin production, promotes angiogenesis (new blood-vessel formation), and has anti-inflammatory properties. The copper component is essential for enzyme function in skin repair.
Outcome
Over the following weeks most people notice better hydration and texture first, plus faster healing of blemishes or post-procedure spots (weeks 1–2), then visibly firmer skin and softer fine lines (weeks 2–4), then deeper renewal — elasticity, thicker hair, faded scarring — through weeks 4–12.
Sources & references
Collagen boost: out-produced vitamin C and retinoic acid
Pickart L, Margolina A. Cosmetics. 2018;5(2):29.
View sourceGHK gene expression: 4,000+ genes shifted toward regeneration
Pickart L, Margolina A. Int J Mol Sci. 2018;19(7):2047.
View sourceGHK-Cu + hyaluronic acid: 25× collagen IV increase
Jiang F et al. J Cosmet Dermatol. 2023;22(9):2598–2604.
View sourceGHK-Cu and skin regeneration mechanisms
Bio Med Research International, 2015
View sourceGHK tripeptide gene-modulating effects
FASEB Journal, 2010
View sourceHair follicle stimulation by copper peptides
Journal of Investigative Dermatology, 2007
View sourceWound healing applications of GHK-Cu
Wound Repair and Regeneration, 2019
View source
Common questions
Important safety information
GHK-Cu is available by prescription only and is dispensed after a licensed provider reviews your medical screening and determines it is appropriate for you. Compounded medications are prepared by a licensed U.S. pharmacy and are not FDA-approved products. Tell your provider about your full medical history and any medications you take.
- • Generally well tolerated
- • Rare skin sensitivity in some individuals
- • Should not be used during pregnancy or breastfeeding
- • Requires licensed provider supervision for injectable form