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Ships fully reconstituted · no mixing, no powder, no bacteriostatic water
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DSIP
Sleep

DSIP

Ships fully reconstituted · no mixing, no powder, no bacteriostatic water

Deep Sleep Peptide

Targets deep delta-wave sleep for restorative rest without next-day grogginess.

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Extra 10% off your first order · use code WELCOME10 at checkout (stacks with the supply discount above).

Physician-reviewed · charged only after your prescription is approved
Free shipping over $350 · compounded in a U.S. pharmacy
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Frequently paired with

What it supports

  • Deeper, more restorative sleep
  • Improved sleep onset
  • Reduced cortisol and stress
  • No next-day grogginess
  • May help with pain perception
  • Natural sleep cycle support
  • Enhanced recovery during sleep

The details

Administration
Subcutaneous injection, evening
Format
1mg/mL, 5mL vial
Typical dosing
100-250mcg before bed
Best for
Deep sleep, sleep efficiency, restorative rest
Pairs well with
Selank, Epitalon, Sermorelin
Mechanism
DSIP modulates the sleep-wake cycle by influencing cortisol rhythms, promoting delta wave sleep, and reducing stress hormones. It works with natural sleep mechanisms rather than forcing sedation, supporting the body's restorative processes.

How it works

Signal

DSIP is given as a single subcutaneous injection in the evening, on a provider-determined schedule.

Cellular response

DSIP modulates the sleep-wake cycle by influencing cortisol rhythms, promoting delta-wave sleep, and lowering stress hormones. It works with your natural sleep mechanisms rather than forcing sedation, supporting the body's restorative processes.

Outcome

Most people notice falling asleep gets easier within the first few nights, with mornings feeling less groggy by weeks 1–2 and genuinely restorative sleep by weeks 2–4. Many keep the improvement for months after finishing a protocol — the unusual part of DSIP’s clinical record.

Sources & references

  • ~59% increase in total sleep time

    Schneider-Helmert D et al. Int J Clin Pharmacol Ther Toxicol. 1981;19(8):341–350.

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  • Chronic insomnia normalized to healthy levels

    Schneider-Helmert D. Eur Neurol. 1987;27(2):108–119.

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  • Normal sleep maintained for months after treatment

    Kaeser HE. Eur Neurol. 1984;23(1):1–4.

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  • DSIP modulation of cortisol and stress response

    Neuroendocrinology, 1988

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  • Sleep-promoting effects of DSIP in humans

    European Neurology, 1986

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  • DSIP and delta-wave EEG activity

    Sleep, 1984

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  • Neuroprotective and antioxidant properties of DSIP

    Bulletin of Experimental Biology and Medicine, 2015

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Common questions

Important safety information

DSIP is available by prescription only and is dispensed after a licensed provider reviews your medical screening and determines it is appropriate for you. Compounded medications are prepared by a licensed U.S. pharmacy and are not FDA-approved products. Tell your provider about your full medical history and any medications you take.

  • Generally well tolerated
  • Possible vivid dreams initially
  • May cause temporary drowsiness
  • Requires licensed provider supervision